Table 2.
Clinical course
| Characteristics | All patients (n = 21) | SSC (n = 5) | nSSC (n = 16) | P |
|---|---|---|---|---|
| Total duration of ventilation (days) |
30.1 ± 48.4 |
88.2 ± 76.4 |
11.9 ± 9.2 |
<0.01 |
| Total days in ICU |
39.6 ± 46.1 |
89.2 ± 75.5 |
30.1 ± 15.2 |
<0.01 |
| ECMO |
|
|
|
|
| Patients treated (%) |
10 (47.6%) |
3 (60%) |
7 (43.8%) |
NS |
| Duration of ECMO (days) |
27.3 ± 20 |
45.7 ± 26 |
19.4 ± 11.5 |
0.05 |
| Survival (%) |
15 (71.4%) |
0 (0%) |
15 (93.8%) |
<0.01 |
| Patients requiring RRT during ICU treatment from day 1 to 28 (%) |
10 (47.6%) |
4 (80%) |
6 (37.5%) |
NS |
| Patients receiving stress-dose steroids (%) |
14 (66.7%) |
5 (100%) |
9 (56.3%) |
<0.01 |
| Mean dosage of norepinephrine day 1 to 7 (μg(kg min)) | 0.13 ± 0.12 | 0.15 ± 0.12 | 0.12 ± 0.11 | NS |
ECMO, extracorporeal membrane oxygenation; NS, non-significant; nSSC, no secondary sclerosing cholangitis; RRT, renal replacement therapy; SSC, secondary sclerosing cholangitis.