Table 2.
Histomorphological features and RACK1 pattern in horse melanocytic lesions
| Scattera | Pigmentb | Nestingc | Circumd | Epid. Contoure | Cell sizef | Cell shapeg | Nuclear sizeh | Nuclear shapei | Nucleolar sizej | Ulcerk | RACK1 patternl | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Melanocytomas |
|
|
|
|
|
|
|
|
|
|
||
|
1 |
3 |
4 |
3 |
- |
- |
3 |
0.5 |
2 |
- |
- |
0 |
1 |
|
2 |
- |
4 |
0 |
- |
- |
2 |
1 |
1 |
- |
1 |
- |
1 |
|
3 |
0 |
1 |
2 |
2 |
2 |
2 |
2 |
2 |
1 |
1 |
0 |
1 |
|
4 |
1 |
3 |
3 |
1 |
4 |
1.5 |
3 |
3 |
1.5 |
1 |
1 |
1 |
|
5 |
1 |
3.5 |
0 |
2 |
2 |
2 |
1 |
1 |
0 |
1 |
0 |
1 |
|
6 |
3 |
4 |
1 |
1 |
2 |
3 |
0.5 |
2 |
0 |
1 |
1 |
1 |
|
7 |
1 |
2 |
2 |
0 |
2 |
3 |
0 |
3 |
0 |
1 |
0 |
1 |
|
8 |
0 |
1 |
1 |
2 |
2 |
3 |
1.5 |
2.5 |
1.5 |
3 |
0 |
1 |
|
9 |
0 |
3 |
1 |
0 |
2 |
3 |
1 |
2 |
0 |
1 |
0 |
1 |
|
10 |
2 |
3 |
1 |
1 |
2 |
2 |
1.5 |
3 |
0 |
1 |
0 |
1 |
|
11 |
1 |
4 |
0 |
1 |
3 |
2.5 |
2.5 |
1 |
1 |
1 |
0 |
1 |
|
12 |
0 |
3.5 |
0 |
0 |
2 |
3 |
1.5 |
2 |
0 |
1 |
1 |
1 |
|
13 |
2 |
4 |
0 |
2 |
3 |
1 |
2 |
3 |
0 |
1 |
0 |
1 |
|
14 |
1 |
4 |
2.5 |
0 |
2 |
2.5 |
1.5 |
2 |
0 |
1.5 |
0 |
1 |
|
15 |
- |
4 |
0 |
1 |
0 |
2 |
1.5 |
2 |
0 |
1 |
1 |
1 |
|
Melanomas |
|
|
|
|
|
|
|
|
|
|
||
|
1 |
3 |
2 |
3 |
1 |
- |
3 |
1 |
3 |
- |
3 |
1 |
0 |
|
2 |
3 |
4 |
2 |
2 |
3 |
3 |
2.5 |
3 |
0 |
1 |
0 |
0 |
|
3 |
2 |
1 |
1 |
2 |
4 |
2 |
2.5 |
3 |
2 |
1 |
1 |
0 |
|
4 |
- |
1 |
0 |
1 |
- |
3 |
1 |
3 |
0 |
3 |
0 |
0 |
|
5 |
3 |
4 |
1 |
1 |
1 |
3 |
1 |
3 |
0 |
2.5 |
1 |
0 |
|
6 |
1 |
4 |
1 |
2 |
3 |
2 |
2 |
3 |
1.5 |
2 |
0 |
0 |
|
7 |
1 |
4 |
3 |
2 |
2 |
3 |
1 |
2.5 |
- |
2 |
0 |
1 |
|
8 |
0 |
3 |
0 |
2 |
2 |
3 |
1 |
3 |
0 |
2.5 |
0 |
1 |
| 9 | 2 | 3 | 2 | 1 | 3 | 3 | 3 | 3 | 1 | 3 | 0 | 0 |
aScatter of intraepidermal melanocytes: 0, absent; 1, slight; 2, medium; 3, prominent.
bCytoplasmic pigmentation of neoplastic melanocytes: 0,absent; 1, slight; 2, medium; 3, high; 4, very high.
cNesting of intraepidermal melanocytes: 0, absent; 1, slight; 2, medium; 3, prominent.
dLateral circumscription: 0, discontinuous; 1, continuous; 2, abrupt.
eEpidermal contour: 0, atrophy; 1, effacement; 2, normal; 3, thickening; 4, hyperplasia.
fCell size: 1, small; 2, medium; 3, large.
gCell shape: 0, round; 1, ovoid; 2, elongated; 3, spindled.
hNuclear size: 1, small; 2, medium; 3, large.
iNuclear shape: 0, round; 1, ovoid; 2, elongated; 3, spindled.
jNucleolar size: 1, small; 2, medium; 3, large.
kUlceration: 0, absent; 1, present.
lRACK1 distribution pattern: 0, homogenous; 1, heterogenous.
-: Impossible evaluation.
x.5: means of two different authors observations.