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. 2012 Oct 22;11:140. doi: 10.1186/1476-511X-11-140

Table 1.

Characteristics of studies investigating LDL-cholesterol lowering effect of plant stanols consumption in doses of 4 g or more

Reference Subject characteristics Treatment characteristics
 
N
Age (years)
Men (%)
weight status
Baseline bloodcholesterol
Study design
Vehicle
Dose of plant stanols (g/d)1
Duration (wk)
[10]Nguyen 1999
83
49
30
 
mildly hypercholesterolaemic
open label, dose-response in comparison to respective baselines
margarine, soya yoghurt
3 / 6 / 10
2
[11]Plat & Mensink 2000
112
33
37
normal
normocholesterolaemic
parallel, randomized, double-blind, placebo-controlled
margarine, shortening for baking
0 / 3.82 / 43
8
[12]Cater et al. 2005
8
58
75
slightly overweight
mildly hypercholesterolaemic
cross-over,randomized, double-blind, placebo-controlled
margarine
0 / 2 / 3 / 4
6
[13]Gylling et al. 2010
49
62
35
slightly overweight
mildly hypercholesterolaemic
parallel, randomized, double-blind, placebo-controlled
margarine, oat based drink
0 / 8.8
10
[14]Mensink et al. 2010 93 56 53 slightly overweight mildly hypercholesterolaemic parallel, randomized, double-blind, placebo-controlled margarine, soya based yoghurt 0 / 3 / 6 / 9 4

1 in each study group, 2vegetable oil based plant stanols, 3 pine wood based plant stanol.