Table 1.
Characteristics of studies investigating LDL-cholesterol lowering effect of plant stanols consumption in doses of 4 g or more
Reference | Subject characteristics | Treatment characteristics | |||||||
---|---|---|---|---|---|---|---|---|---|
|
N |
Age (years) |
Men (%) |
weight status |
Baseline bloodcholesterol |
Study design |
Vehicle |
Dose of plant stanols (g/d)1 |
Duration (wk) |
[10]Nguyen 1999 |
83 |
49 |
30 |
|
mildly hypercholesterolaemic |
open label, dose-response in comparison to respective baselines |
margarine, soya yoghurt |
3 / 6 / 10 |
2 |
[11]Plat & Mensink 2000 |
112 |
33 |
37 |
normal |
normocholesterolaemic |
parallel, randomized, double-blind, placebo-controlled |
margarine, shortening for baking |
0 / 3.82 / 43 |
8 |
[12]Cater et al. 2005 |
8 |
58 |
75 |
slightly overweight |
mildly hypercholesterolaemic |
cross-over,randomized, double-blind, placebo-controlled |
margarine |
0 / 2 / 3 / 4 |
6 |
[13]Gylling et al. 2010 |
49 |
62 |
35 |
slightly overweight |
mildly hypercholesterolaemic |
parallel, randomized, double-blind, placebo-controlled |
margarine, oat based drink |
0 / 8.8 |
10 |
[14]Mensink et al. 2010 | 93 | 56 | 53 | slightly overweight | mildly hypercholesterolaemic | parallel, randomized, double-blind, placebo-controlled | margarine, soya based yoghurt | 0 / 3 / 6 / 9 | 4 |
1 in each study group, 2vegetable oil based plant stanols, 3 pine wood based plant stanol.