Table 2.
Correlation of lipid and apolipoprotein parameters with CAD in various lipidemic groups
| |
NL |
|
HTGa |
|
HCb |
|
HLPc |
|
||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (n=40) | (n=15) | (n=59) | (n=11) | (n=36) | (n=29) | (n=65) | (n=35) | |||||
|
CAD |
– |
+ |
|
– |
+ |
|
– |
+ |
|
– |
+ |
|
| |
|
|
Pvalue |
|
|
Pvalue |
|
|
Pvalue |
|
|
Pvalue |
|
TG |
78.9±17.3 |
101.4±26.0 |
NS |
345.4±15.0 |
396.0±33.6 |
NS |
90.4±17.5 |
110.2±19.8 |
NS |
391.5±12.9 |
333.2±17.5 |
0.008 |
|
TC |
160.6±5.8 |
175.8±8.7 |
NS |
171.7±5.0 |
178.3±11.3 |
NS |
275.4±5.9 |
261.6±6.6 |
NS |
280.9±4.3 |
272.6±5.9 |
NS |
|
LDL-C |
103.2±6.3 |
119.8±9.5 |
NS |
120.8±5.5 |
104.1±12.3 |
NS |
210.1±6.4 |
201.6±7.2 |
NS |
219.3±4.7 |
199.2±6.5 |
0.01 |
|
HDL-C |
47.5±1.7 |
35.8±2.6 |
0.0004 |
38.0±1.5 |
26.4±3.4 |
0.0025 |
53.2±1.8 |
38.6±2.0 |
0.0001 |
39.5±1.3 |
36.2±1.8 |
NS |
|
Lp(a) |
2.19±0.39 |
4.41±0.26 |
0.0001 |
3.38±0.22 |
3.69±0.87 |
NS |
4.54±0.26 |
3.23±0.33 |
0.001 |
4.34±0.19 |
4.86±0.35 |
NS |
|
ApoAI |
122±4.9 |
95.9±6.7 |
0.002 |
127±5.5 |
108±8.6 |
NS |
138±4.5 |
107±5.0 |
0.001 |
135±3.4 |
114±4.5 |
0.0003 |
|
ApoB |
75±5.3 |
79±7.3 |
NS |
85.6±6.0 |
127±9.4 |
0.0002 |
113±4.9 |
114±5.5 |
NS |
142±3.7 |
152±4.9 |
NS |
|
ApoCIII |
14.5±0.9 |
18.4±1.3 |
0.02 |
16.8±0.8 |
16.0±1.7 |
NS |
21.3±0.9 |
17.9±1.0 |
0.01 |
22.4±0.6 |
16.5±0.9 |
0.0001 |
| ApoE | 3.33±0.34 | 2.96±0.52 | NS | 4.30±0.30 | 6.63±0.67 | 0.002 | 4.18±0.35 | 3.79±0.33 | NS | 4.98±0.26 | 6.13±0.37 | 0.01 |
Data are presented as mean ± standard error of the mean, and all units are mg/dL.
CAD = coronary artery disease; NL = normolipidemic; HTG = hypertriglyceridemic; HC = hypercholesterolemic; HLP = hyperlipidemic; TG = triglyceride; NS = nonsignificant; TC = total cholesterol; LDL-C = low-density lipoprotein cholesterol; HDL-C = high-density lipoprotein cholesterol; Lp(a) = lipoprotein (a); Apo = apolipoprotein.
aTG >150 mg/dL.
bTC >200 mg/dL.
cHC + HTG.