Table 4.
Odds ratios and 95% confidence intervals for predicting CAD in various lipidemic groups and in all subjects
| Odds Ratio | 95%CI | Pvalue | |
|---|---|---|---|
|
NL Groupa |
|
|
|
| HDL-ApoCIII |
1.49 |
1.12–1.99 |
0.006 |
| VLDL-ApoCIII |
0.74 |
0.53–1.01 |
0.06 |
| HDL-ApoCIII/ VLDL-ApoCIII |
1.85 |
1.14–2.89 |
0.01 |
| Men |
2.76 |
1.57–3.48 |
0.005 |
| Women |
1.65 |
1.06–2.33 |
0.02 |
| ApoAI |
0.62 |
0.46–0.84 |
0.002 |
|
HTG Groupa |
|
|
|
| HDL-ApoCIII |
2.00 |
1.05–3.80 |
0.04 |
| VLDL-ApoCIII |
0.79 |
0.45–1.41 |
0.43 |
| HDL-ApoCIII/ VLDL-ApoCIII |
2.52 |
0.76–5.98 |
0.02 |
| Men |
3.17 |
1.14–3.94 |
0.005 |
| Women |
1.55 |
1.04–1.89 |
0.03 |
|
HC Groupa |
|
|
|
| HDL-ApoCIII |
1.56 |
1.18–2.05 |
0.002 |
| VLDL-ApoCIII |
0.74 |
0.61–0.90 |
0.003 |
| HDL-ApoCIII/ VLDL-ApoCIII |
1.78 |
1.23–2.67 |
0.003 |
| Men |
1.96 |
1.26–2.67 |
0.005 |
| Women |
1.23 |
1.06–1.89 |
0.01 |
| ApoAI |
0.72 |
0.55–0.93 |
0.01 |
|
HLP Groupa |
|
|
|
| HDL-ApoCIII |
0.90 |
0.64–1.28 |
0.57 |
| VLDL-ApoCIII |
0.66 |
0.54–0.81 |
<0.0001 |
| HDL-ApoCIII/ VLDL-ApoCIII |
1.57 |
1.01–2.24 |
0.01 |
| Men |
1.80 |
1.26–2.72 |
0.004 |
| Women |
1.25 |
0.94–1.88 |
0.02 |
| TG |
0.96 |
0.94–0.99 |
0.005 |
| TC |
1.16 |
1.04–1.30 |
0.006 |
| LDL-C |
0.83 |
0.73–0.94 |
0.004 |
| ApoAI |
0.21 |
0.07–0.68 |
0.009 |
|
All Subjects, Final Modelb |
|
|
|
| HDL-ApoCIII/ VLDL-ApoCIII |
2.04 |
1.46–2.84 |
<0.0001 |
| Female sex |
0.26 |
0.10–0.66 |
0.0043 |
| Age |
1.06 |
1.02–1.10 |
0.0063 |
| TC |
1.04 |
1.01–1.06 |
0.002 |
| TG |
0.99 |
0.99–1.00 |
<0.0001 |
| LDL-C |
0.99 |
0.98–1.00 |
0.01 |
| HDL-C |
0.95 |
0.90–1.00 |
0.03 |
| ApoB |
1.46 |
1.25–1.70 |
<0.0001 |
| ApoAI | 0.66 | 0.55–0.80 | <0.0001 |
CAD = coronary artery disease; CI = confidence interval; NL = normolipidemic; HDL = high-density lipoprotein; VLDL = very-low-density lipoprotein; Apo = apolipoprotein; HTG = hypertriglyceridemic; HC = hypercholesterolemic; HLP = hyperlipidemic; TG = triglyceride; TC = total cholesterol; LDL-C = low-density lipoprotein cholesterol.
aThe following co-variables were entered in the multivariate regression model: TG, TC, ApoAI, ApoB, ApoCIII, ApoE, LDL-C, HDL-C, HDL-ApoE, VLDL-ApoE, and forced entry of HDL-ApoCIII and VLDL-ApoCIII.
bThe following co-variables were entered in the multivariate regression model: TG, TC, ApoAI, ApoB, Lp(a), ApoCIII, ApoE, LDL-C, HDL-C, HDL-ApoE, VLDL-ApoE and HDL-ApoCIII/VLDL-ApoCIII ratio.