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. 2013 Jan 11;8(1):e54173. doi: 10.1371/journal.pone.0054173

Figure 3. Expression analysis of pancreatic endocrine hormones.

Figure 3

Images show immuno-stainings for insulin (A, B), glucagon (C, D), and somatostatin (E, F) in sections through the pancreas of control (A, C, E) and CPTD6 (B, D, F) mice sacrificed 5 weeks post-injections. Insulin expression is almost completely abolished in CPTD6 islets compared with control islets (A, B). The number of cells staining positive for glucagon is also decreased in the CPTD6 islets compared to controls (C, D). Somatostatin expression is more moderately reduced in the CPTD6 islets with most CPTD6 islets showing fewer positive cells compared to the controls. (E, F). Images are representative of at least four animals from each group. Scale bar, 50 µm.