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Increased susceptibility to EAE in PDLIM2 deficient mice.A) Incidence, B) disease progression, C) severity and D) onset of EAE in PDLIM2+/+ and PDLIM2−/− mice (n = 15). Mice were immunized with PLP180–199 peptide and monitored daily for EAE disease symptoms. The p values between the PDLIM2+/+ (WT) and PDLIM2−/− (KO) groups are at least smaller than 0.05 by two tailed t-test.
