Figure 3.

Increased severity of adoptive transfer EAE in recipients of PDLIM2 deficient CD4⁺T cells. CD4⁺ T cells were isolated from PDLIM2^+/+ and PDLIM2^−/− mice immunized with PLP_180–199 peptide and transferred i.v. into SCID recipients (n = 20). One day after the cell transfer, recipient mice also received an injection of pertussis. Mice were then monitored for the symptoms of EAE as described in Figure .2