Figure 3.

Effect of fraction of cells labeled on the shape of the survival curve for the mixed cell population (labeled + unlabeled) when a 100-keV monoenergetic electron emitter is uniformly distributed among the labeled cells. The surviving fraction of mixed cells is plotted as a function of mean absorbed dose to all cell nuclei. The survival curves are shown for four different labeled fractions: 100%, 50%, 10%, and 1%. The lower and upper dashed lines represent exponential survival curves with D₃₇ = D_37,self = 1.2 Gy and D₃₇ = D_37,cross = 4.0 Gy, respectively. A complete set of curves for all combinations of energy and fraction of cells labeled is provided in Fig. 3 of the supplementary material (B) (Ref. ⁵⁰). For the sake of comparison, the data for 100% labeling are reproduced from Rajon et al. (Ref. ³²).