Table 4. Screening test performance: estimated corrected positive predictive value and negative predictive values.

	CIN2+ (N = 310)		CIN3+ (N = 102)
	PPV 95% CI	NPV 95% CI	PPV 95% CI	NPV 95% CI
Cytology*	64.5% (59.7–69.3)	89.7% (87.3–92.1)	25.7% (21.3–30.1)	99.2% (98.6–99.9)
VIA	48.5% (44.0–53.0)	87.5% (84.6–90.3)	15.7% (12.4–18.9)	96.1% (94.6–97.6)
HPV	42.9% (39.0–46.8)	94.1% (91.5–96.7)	14.6% (11.9–17.3)	99.5% (98.8–100)
Combined Cytology/VIA	47.3% (43.4–51.3)	93.4% (90.9–96.0)	16.6% (13.6–19.5)	99.5% (98.8–100)
Combined Cytology/HPV	42.2% (38.5–45.8)	95.5% (93.1–98.0)	14.3% (11.7–16.9)	100% (99.9–100)
Combined HPV/VIA	39.8% (36.3–43.3)	96.0% (93.4–98.6)	13.2% (10.8–15.6)	99.7% (99.1–100)
Combined Cytology/VIA/HPV	40.8% (37.3–44.3)	96.4% (93.7–99.0)	13.8% (11.3–16.2)	100% (99.8–100)

CIN2+ = CIN2/CIN3/ICC, CIN3+ = CIN3/ICC, PPV = Positive predictive value, NPV = Negative predictive value, CI = Confidence interval, Cytology = Cytology Pap smear, HPV = HPV DNA, VIA = Visual inspection with 5% acetic acid.

^*Cytology negative: normal/LSIL/ASCUS; positive: HSIL, ASC-H, SCC.