Figure 3. Modular relationship among plasmid-encoded replication proteins.

Horizontal bars represent replication proteins with distinct domains indicated with different colours – the primase-polymerase domain is shown in blue, the C-terminal domain of pTN2 replicase is in red, and the winged helix-turn-helix domain is in green. The numbers above the bars represent the amino acid coordinates of the depicted domains in the replicases of respective plasmids (plasmid names are on the right). The numbers next to the plasmid names denote how many additional plasmids encode the specific type of a replication protein.