Table 1. Initial characteristics and neuropsychological performances of OCD patients and healthy controls.
Variable | OCD patients (n = 15) | Healthy controls (n = 15) | p-value |
Demographic characteristics | |||
Sex ratio (female/male) | 5/10 | 5/10 | NA |
Age (years) | 36+/−13 | 37+/−13 | NA |
Education (years) | 13+/−2 | 12+/−2 | NA |
Clinical characteristics | |||
Y-BOCS | 27.4+/−5.7 | NA | NA |
GAF | 33+/−3 | NA | NA |
CGI | 5+/−1 | NA | NA |
Mattis | 138+/−4 | 140+/−2 | 0.142 |
MADRS | 12+/−8 | 1+/−2 | <0.001 |
Neuropsychological performance | |||
Hopkins Test total (score) | 24.8+/−5.2 | 27.7+/−4.4 | 0.070 |
Hopkins Test delayed recall (score) | 9.3+/−2.1 | 9.4+/−2.5 | 0.838 |
Hopkins Test recognition (score) | 11.3+/−1.0 | 11.3+/−1.3 | 0.873 |
Word fluency v (n) | 14.4+/−4.3 | 17.7+/−4.7 | 0.052 |
Word fluency p (n) | 21.9+/−6.0 | 22.9+/−7.0 | 0.718 |
Word fluency animals (n) | 31.1+/−7.5 | 38.9+/−7.7 | 0.009 |
RCFT copy (score) | 35.2+/−1.1 | 35.7+/−0.7 | 0.089 |
RCFT immediate recall (score) | 20.4+/−9.2 | 23.1+/−8.0 | 0.441 |
RCFT recall delayed (score) | 20.0+/−9.3 | 22.1+/−7.2 | 0.534 |
TMT A correct answers (n) | 25+/−0 | 25+/−0 | NA |
TMT A time (s) | 31.7+/−15.4 | 25.7+/−8.4 | 0.164 |
TMT B correct answers (n) | 24.5+/−1.1 | 24.5+/−1.4 | 1.000 |
TMT B time (sec) | 89.4+/−55.6 | 69.6+/−35.0 | 0.245 |
TMT B-A answers (n) | −0.5+/−1.1 | −0.5+/−1.4 | 1.000 |
TMT B-A time (s) | 57.7+/−46.8 | 43.9+/−32.5 | 0.336 |
OAT number trials needed (n) | 29.5+/−14.7 | 23.5+/−12.1 | 0.222 |
OAT correct answers (n) | 21.7+/−9.1 | 17.7+/−6.4 | 0.152 |
OAT errors (n) | 7.7+/−6.7 | 5.8+/−6.1 | 0.425 |
Stroop test colour (n) | 79.4+/−12.2 | 90.2+/−8.8 | 0.002 |
Stroop test reading (n) | 97.9+/−4.7 | 100.6+/−11.9 | 0.417 |
Stroop test colour/reading (n) | 52.5+/−19.3 | 67.6+/−13.5 | 0.003 |
Stroop interference (index) | 9.5+/−15.7 | 20.6+/−12 | 0.009 |
Tower of London (n) | 15.2+/−4.8 | 15.8+/−2.2 | 0.825 |
Tower of London total time (s) | 448+/−170 | 330+/−76 | 0.028 |
Tower of London time first shot (s) | 118+/−79 | 78+/−37 | 0.068 |
RCFT: Rey-Osterrieth Complex Figure Test.
TMT: Trail Making Test.
OAT: Object Alternation Task.
NA: Not applicable (either because no measure was available for healthy controls or because patients and controls were matched for these variables).