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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Diabetologia. 2012 Jul 22;55(10):2682–2692. doi: 10.1007/s00125-012-2650-x

Fig. 6.

Fig. 6

PKD1 is necessary for oleate-mediated F-actin depolymerisation. (a) Representative images for F-actin staining (red) for each incubation condition with intensity line scans for F-actin staining intensity. Dashed lines represent the F-actin intensity means for the 2.8 G condition. Beta cells were identified by insulin staining (blue). (b) Mean±SEM F-actin intensities from 20–35 cells, from three mice, of Ad-GFP (white bars)- or Ad-Cre (black bars)-infected Prkd1flox/flox islets. a.u., arbitrary units; Latr, latrunculin. ***p<0.001 compared with the 2.8 mmol/l glucose (2.8 G) condition for each condition; †p<0.001 compared with the respective condition in Ad-GFP