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Central administration of αCGRP increases, and CGRP8–37 decreases, depression-like behavior in the FST in F1 mice bred from cJ females and B6 males. CGRP8–37 reduced immobility compared to vehicle (a). Neither αCGRP nor CGRP8–37 altered swimming (b). αCGRP reduced climbing compared to vehicle and CGRP8–37 (c). Bars represent mean ± SEM (n=8–12 per group).
