Table II.
Comparison of Demographic and Clinical Information for Participants in Total Sample With and Those Without Explosive Outbursts
| Do Not Have Explosive Outbursts(N=174) |
Have Explosive Outbursts(N=44) |
(X2/t, P- value)* |
|
|---|---|---|---|
| Percent US participants | 75.4%(N=86) | 24.6%(N=28) | |
| Percent CR participants | 84.6%(N=88) | 15.4%9N=16) | (2.84, 0.09) |
| Percent Male | 75.9% (N=132) | 88.6% (N=39) | (3.39, 0.07) |
| Mean age at interview (SD) | 18.1 (13.2) | 16.9 (10.9) | (0.57, 0.57) |
| Socioeconomic status (Hollingshead score = 1) | 10.4%(N=18) | 4.4%(N=2) | |
| Socioeconomic status (Hollingshead score = 2) | 30.4%(N=53) | 34.8%(N=15) | |
| Socioeconomic status (Hollingshead score = 3) | 28.8%(N=50) | 34.8%(N=15) | |
| Socioeconomic status (Hollingshead score = 4) | 24.0%(N=42) | 21.7%(N=9) | |
| Socioeconomic status (Hollingshead score = 5) | 6.4%(N=11) | 4.4%(N=2) | (1.28, 0.6) |
| Referred to study by medical professional | 50% (N=85) | 63.6% (N=28) | (2.62, 0.11) |
| Mean age at onset of tic symptoms (SD) | 6.1 (2.5) | 4.8 (1.9) | (3.17, <0.001) |
| Mean age at onset of OC symptoms (SD) | 6.9 (4.0) | 7.7 (4.5) | (−0.94, 0.35) |
| Mean age of onset of ADHD symptoms (SD) | 4.9 (2.1) | 4.3 (2.6) | (1.31, 0.19) |
| Family history of tics (N=199) | 76.1%(N=121) | 85% (N=34) | (1.47, 0.23) |
| Maternal family history of tics (N=164) | 46.2% (N=61) | 59.4% (N=19) | (1.79, 0.18) |
| Paternal family history of tics (N=181) | 55.2% (N=79) | 63.2% (N=24) | (0.77, 0.38) |
| Self injurious behavior | 19.8% (N=34) | 29.6% (N=13) | (1.97, 0.16) |
| Severe self injurious behavior | 1.8% (N=3) | 4.6% (N=2) | (F, 0.27)* |
| Mean tic severity (motor and phonic tic YGTSS scores) (SD) |
33.2 (8.4) | 37.3 (7.2) | (−2.98, 0.001) |
| Maternal tobacco use during pregnancy | 4.1% (N=7) | 11.4% (N=5) | (3,60, 0.058) |
| Maternal alcohol and illicit drugs during | 1.7% (N=3) | 2.3% (N=1) | (F, 1.00)* |
| pregnancy | |||
| Medications during pregnancy | 21.2% (N=36) | 14.0% (N=6) | (1.13, 0.29) |
| Prenatal complications | 12.7% (N=22) | 9.1% (N=4) | (0.44, 0.51) |
| Nuchal cord/Hypoxia | 9.3% (N=16) | 9.1% (N=4) | (F,1.00)* |
| Forceps/Suction delivery | 9.3% (N=16) | 6.8% (N=3) | (F, 0.77)* |
| Emergency C−Section | 17.9% (N=31) | 29.6%(N=13) | (2.93, 0.09) |
| Traumatic delivery | 10.5% (N=18) | 15.9% (N=7) | (1.01, 0.31) |
| Jaundice | 17.3% (N=30) | 15.9% (N=7) | (0.05, 0.82) |
| Premature labor | 9.8% (N=17) | 22.7%(N=5) | (F, 0.78)* |
| Fertility drugs | 1.7% (N=3) | 4.6% (N=2) | (F, 0.27)* |
| Twin birth | 50.0%(N=87) | 50.0%(N=22) | (F, 0.18) * |
| Birth weight (lbs) | 7.14(1.3) | 7.2 (1.3) | (−0.26, 0.80) |