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A: core body temperature of 12-mo-old rats after being placed in a 4°C chamber at time 0. Control animals raised their core temperature significantly more than did RH animals (P < 0.001 for interaction between group and time). B: uncoupling protein 1 (UCP1) mRNA in the brown adipose tissue (BAT) of 12-mo-old rats, standardized to β-actin expression. UCP1 mRNA was significantly higher in BAT from control animals than from RH animals, P < 0.01.
