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. 2012 Nov 7;304(1):F103–F111. doi: 10.1152/ajprenal.00385.2012

Fig. 4.

Fig. 4.

The effect of diabetes (DM) on the abundance of phosphorylated AQP2. A: phosphorylated (p) serine (ser) 256-AQP2 abundance is decreased in response to DM in the UT-A1/A3 KO mice compared with the WT diabetic mice. Top, Western blot of tissue lysate from WT and UT-A1/A3 KO mice, with and without diabetes, probed for pser256-AQP2. Bottom, bar graph showing combined mean densities ± SE from 2 experiments; n = 4/condition. *P ≤ 0.05. NS, not significant. B: pser261-AQP2 abundance is decreased in response to diabetes in the UT-A1/A3 KO mice compared with the WT diabetic mice. Top, Western blot of tissue lysate from WT and UT-A1/A3 KO, with and without diabetes, probed with pser261-AQP2. Each lane is loaded with a sample from a different rat. Immediately below is the loading control (LC). Bottom, bar graph showing combined mean densities ± SE from 2 experiments; n = 4/condition. *P ≤ 0.01.