Table 2.

Fetal measurements and organ weights

	Control	Hypoglycemic	HG+I
Gestational age, day	133.2 ± 1.1	133.0 ± 1.3	134.5 ± 0.9
Fetal weight, kg	3.66 ± 0.12	2.20 ± 0.14‡	2.61 ± 0.2†
Organ weights, g
Liver	137.8 ± 13.2	76.3 ± 5.5†	104.2 ± 13.7
Heart	31.1 ± 0.4	18.6 ± 1.8†	22.4 ± 2.8*
Lungs	120.5 ± 8.7	82.6 ± 6.6*	87.4 ± 8.8*
Kidneys	24.2 ± 1.0	16.9 ± 1.0†	17.3 ± 1.4*
Spleen	14.3 ± 2.0	6.6 ± 0.8†	7.0 ± 1.0*
Adrenals	0.4 ± 0.1	0.4 ± 0.1	0.5 ± 0.1
Brain	46.1 ± 2.7	44.1 ± 2.2	40.7 ± 1.6
Pancreas	4.3 ± 0.8	2.8 ± 0.2*	2.5 ± 0.4*
Placenta	379.5 ± 25.7	294.2 ± 37.7	247.6 ± 22.6*
Lower limb length, cm	35.3 ± 1.2	30.1 ± 1.4*	29.9 ± 1.3*

All values are means ± SE.

^*P < 0.05;

^†P < 0.005;

^‡P < 0.0001. Control vs. Hypoglycemic or HG+I. HG+I, hypoglycemic + insulin. Gestational age refers to age at organ isolation. Glucose-stimulated insulin secretion was measured 1 day earlier. Fetal age, weight, and liver weight have been previously published (78).