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Effect of etanercept on litter size and pup weights in NP and RUPP pregnant rats. Pup weights (B) were significantly reduced in response to RUPP, whereas litter size (A) remained unaffected. Treatment with etanercept had no effect on litter size or pup weight. Data were analyzed by ANOVA followed by Tukey's post hoc test and are shown as means ± SE.
