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Effect of exogenous TNF-α on placental sFlt-1 production. NP placental explants were cultured in the presence of exogenous TNF-α (0.01, 0.1, 1, and 10 ng/ml). sFlt-1 production was unaltered in the presence of exogenous TNF-α under normoxic conditions compared with untreated NP control explants. Data are analyzed using ANOVA followed by Tukey's post hoc test, and data are expressed as means ± SE.
