Table 1.

Effect of ATRA on blood pressure and HR in SD rats

		ATRA
Parameter	Basal	10 min	20 min
SBP, mmHg	124.3 ± 6.6	113.0 ± 11.2	104.3 ± 10.3*
DBP, mmHg	97.3 ± 8.5	87.3 ± 9.6	81.3 ± 6.1*
MAP, mmHg	108.8 ± 7.6	99.0 ± 9.3	90.3 ± 8.7*
HR, beats/min	362.3 ± 5.3	357.0 ± 3.7	346.0 ± 3.1*

Values are means ± SE; n = 4 Sprague-Dawley (SD) rats. ATRA, all-trans-retinoic acid; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial blood pressure; HR, heart rate.

^*P < 0.01 vs. basal.