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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Breast Cancer Res Treat. 2012 Dec 22;137(2):493–502. doi: 10.1007/s10549-012-2385-x

Table 2.

Statistically significant clusters from imaging analyses (voxel-level p uncorrected = 0.001, cluster size = 10 voxels for all analyses).

Peak MNI coordinates (x y z) Cluster extent (k) Cluster-level pcorrected (FWE) Cluster-level puncorrected Z Region description of local maxima within cluster Brodmann Area (BA)
VBM: Positive correlation with post-chemotherapy interval
9 9 42 79 0.996 0.465 4.15 Right cingulate gyrus 32
64 8 8 160 0.970 0.294 4.10 Right precentral gyrus 44
37 37 33 608 0.453 0.051 4.09 Right superior and middle frontal gyri 9, 10
20 21 5 73 0.997 0.484 3.63 Right caudate N/A
−8 16 47 48 0.999 0.577 3.50 Left cingulate gyrus 32
−21 11 −23 105 0.991 0.396 3.44 Left inferior frontal gyrus 47
−21 20 2 11 >0.999 0.814 3.44 Left putamen N/A
15 −80 33 26 >0.999 0.694 3.42 Right precuneus 7
−9 83 14 37 0.999 0.630 3.38 Left cuneus 18
64 −20 −2 40 0.998 0.615 3.35 Right superior temporal gyrus 21
3-back > 0-back: Negative correlation with post-chemotherapy interval
40 52 16 16 0.922 0.095 3.84 Right middle frontal gyrus 10
VBM: Healthy Control > Breast Cancer Survivor
−43 −67 8 143 0.971 0.411 3.67 Left middle temporal gyrus 37
16 −26 −4 188 0.948 0.344 3.60 Right midbrain N/A
−14 −23 6 408 0.762 0.167 3.58 Left thalamus N/A
2 −23 −17 184 0.950 0.349 3.53 Right midbrain N/A
38 −66 −39 461 0.709 0.143 3.48 Right cerebellum N/A
49 −21 23 59 0.995 0.611 3.37 Right insula 13
3-back > 0-back: Healthy Control > Breast Cancer Survivor
10 −68 42 23 0.808 0.080 3.56 Right precuneus 7
−28 −66 22 15 0.954 0.150 3.47 Left middle temporal gyrus 39