Table 2.
Statistically significant clusters from imaging analyses (voxel-level p uncorrected = 0.001, cluster size = 10 voxels for all analyses).
| Peak MNI coordinates (x y z) | Cluster extent (k) | Cluster-level pcorrected (FWE) | Cluster-level puncorrected | Z | Region description of local maxima within cluster | Brodmann Area (BA) |
|---|---|---|---|---|---|---|
| VBM: Positive correlation with post-chemotherapy interval | ||||||
| 9 9 42 | 79 | 0.996 | 0.465 | 4.15 | Right cingulate gyrus | 32 |
| 64 8 8 | 160 | 0.970 | 0.294 | 4.10 | Right precentral gyrus | 44 |
| 37 37 33 | 608 | 0.453 | 0.051 | 4.09 | Right superior and middle frontal gyri | 9, 10 |
| 20 21 5 | 73 | 0.997 | 0.484 | 3.63 | Right caudate | N/A |
| −8 16 47 | 48 | 0.999 | 0.577 | 3.50 | Left cingulate gyrus | 32 |
| −21 11 −23 | 105 | 0.991 | 0.396 | 3.44 | Left inferior frontal gyrus | 47 |
| −21 20 2 | 11 | >0.999 | 0.814 | 3.44 | Left putamen | N/A |
| 15 −80 33 | 26 | >0.999 | 0.694 | 3.42 | Right precuneus | 7 |
| −9 83 14 | 37 | 0.999 | 0.630 | 3.38 | Left cuneus | 18 |
| 64 −20 −2 | 40 | 0.998 | 0.615 | 3.35 | Right superior temporal gyrus | 21 |
| 3-back > 0-back: Negative correlation with post-chemotherapy interval | ||||||
| 40 52 16 | 16 | 0.922 | 0.095 | 3.84 | Right middle frontal gyrus | 10 |
| VBM: Healthy Control > Breast Cancer Survivor | ||||||
| −43 −67 8 | 143 | 0.971 | 0.411 | 3.67 | Left middle temporal gyrus | 37 |
| 16 −26 −4 | 188 | 0.948 | 0.344 | 3.60 | Right midbrain | N/A |
| −14 −23 6 | 408 | 0.762 | 0.167 | 3.58 | Left thalamus | N/A |
| 2 −23 −17 | 184 | 0.950 | 0.349 | 3.53 | Right midbrain | N/A |
| 38 −66 −39 | 461 | 0.709 | 0.143 | 3.48 | Right cerebellum | N/A |
| 49 −21 23 | 59 | 0.995 | 0.611 | 3.37 | Right insula | 13 |
| 3-back > 0-back: Healthy Control > Breast Cancer Survivor | ||||||
| 10 −68 42 | 23 | 0.808 | 0.080 | 3.56 | Right precuneus | 7 |
| −28 −66 22 | 15 | 0.954 | 0.150 | 3.47 | Left middle temporal gyrus | 39 |