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. 2012 Nov 29;12:239. doi: 10.1186/1472-6882-12-239

Table 10.

Semi-quantitative histological analysis on effect of drug intervention against liver fibrosis induced by BDL in rats(n = 7,x¯±s)

Group Hepatocyte death Inflammatory cell infiltration Fibrosis Combined score
Normal
0.5 ± 0.3
0.3 ± 0.3
0.5 ± 0.1
0.5 ± 0.3
Shamed
0.8 ± 0.3
0.7 ± 0.4
0.5 ± 0.3
0.8 ± 0.3
Model
4.7 ± 0.8△△
4.7 ± 0.4△△
5.5 ± 0.7△△
4.8 ± 0.6△△
Sylimarin
3.5 ± 0.3*
4.4 ± 0.9
4.5 ± 0.6
4.2 ± 0.5
Berberine
2.4 ± 0.5**
2.3 ± 0.7**
2.7 ± 0.7**
2.5 ± 0.6**
CRAE
2.7 ± 0.4**
3.4 ± 0.9*
3.3 ± 0.3**
3.0 ± 0.3**
Bear Bile
3.9 ± 0.1
3.5 ± 0.4**
3.3 ± 0.6**
3.8 ± 0.4*
TUDCA 2.8 ± 0.3** 3.7 ± 0.2** 3.6 ± 0.2** 3.4 ± 0.2**

p < 0.05 when compared with normal group; △△p < 0.01 when compared with normal group; *p < 0.05 when compared with model group; **p < 0.01 when compared with model group.