Table 4.

Impact of drug intervention on the animal daily behavior in alcohol fed-induced liver fibrotic rats (n = 7,$\overline{x}\pm s$)

Index			Body weight (g)				Water drinking (mL per rat)				feeding (g per rat)
Group	dose mg/kg	n	D35	D42	D49	D56	D35	D42	D49	D56	D35	D42	D49	D56
Normal	—	7	399 ± 24.8	391 ± 27.6	435 ± 15.4	440 ± 13.9	33.8 ± 8.84	48.1 ± 0.88	42.5 ± 8.84	44.1 ± 0.18	24.5 ± 2.81	30.6 ± 7.78	27.2 ± 2.83	28.5 ± 2.76
Model	—	7	296 ± 33.6△△	272 ± 30.1△△	293 ± 33.8△△	326 ± 49.4△△	39.3 ± 5.48	37.0 ± 8.31	37.4 ± 4.40	35.8 ± 15.8	21.8 ± 3.87	17.7 ± 6.74	16.3 ± 6.07	21.7 ± 5.34
Silymarin	150	7	321 ± 33.3	317 ± 47.9**	357 ± 45.4**	378 ± 43.1**	41.3 ± 17.7	49.2 ± 13.0*	55.3 ± 0.47**	56.0 ± 6.66*	24.2 ± 6.08	13.8 ± 8.22	23.4 ± 1.61	25.0 ± 0.08
Berberine	120	7	278 ± 27.1	281 ± 30.7	296 ± 31.3	304 ± 35.8	31.2 ± 5.07	42.5 ± 15.2	34.1 ± 2.79	29.8 ± 3.06	18.0 ± 6.28	14.6 ± 2.31	19.0 ± 6.15	18.1 ± 3.20
CRAE	600	7	287 ± 18.9	280 ± 28.3	303 ± 30.5	316 ± 42.8	36.6 ± 2.88	40.9 ± 7.1	33.4 ± 15.16	37.3 ± 15.8	21.6 ± 3.53	14.9 ± 4.33	16.6 ± 6.61	24.2 ± 18.98
Bear bile	200	7	279 ± 28.0	263 ± 28.3	279 ± 35.4	302 ± 44.8	29.6 ± 6.07	41.5 ± 12.4	31.4 ± 11.20	35.9 ± 11.0	18.6 ± 5.49	21.1 ± 13.6	17.2 ± 5.74	21.4 ± 4.96
TUDCA	20	7	308 ± 48.2	291 ± 56.7	324 ± 30.6	362 ± 30.5	32.5 ± 0.35	42.5 ± 15.9	40.5 ± 7.42	37.0 ± 4.24	19.8 ± 3.32	24.3 ± 11.8	22.3 ± 3.59	20.6 ± 1.31

^△p < 0.05 when compared with normal group; ^△△p < 0.01 when compared with normal group; ^*p < 0.05 when compared with model group; ^**p < 0.01 when compared with model group.