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. 2012 Nov 29;12:239. doi: 10.1186/1472-6882-12-239

Table 9.

Semi-quantitative histological analysis on effect of drug intervention against liver fibrosis induced by CCl4in rats(n = 7,x¯±s)

Group Hepatocyte death Inflammatory cell infiltration Fibrosis Combined score
Normal
0.8 ± 0.3
0.3 ± 0.2
0.3 ± 0.2
0.5 ± 0.1
Model
5.6 ± 0.9△△
3.9 ± 0.4△△
3.3 ± 0.6△△
4.8 ± 0.7△△
Sylimarin
3.9 ± 0.2*
2.8 ± 0.6*
2.3 ± 0.6
3.0 ± 0.9*
Berberine
3.5 ± 0.4*
3.1 ± 0.4
2.0 ± 0.5*
3.0 ± 0.6*
CRAE
3.8 ± 0.4*
3.0 ± 0.3*
2.1 ± 0.4*
3.2 ± 0.5*
Bear Bile
3.1 ± 0.3**
2.7 ± 0.7*
2.4 ± 0.5
2.8 ± 0.5**
TUDCA 4.3 ± 0.7 3.5 ± 0.4 2.8 ± 0.2 4.1 ± 0.4

p < 0.05 when compared with normal group; △△p < 0.01 when compared with normal group; *p < 0.05 when compared with model group; **p < 0.01 when compared with model group.