Table 1.
SAMR1 | SAMP8 | |||||
---|---|---|---|---|---|---|
3 months | 6 months | 10 months | 3 months | 6 months | 10 months | |
Body weight (g) | 23.7 ± 0.2 | 26.7 ± 0.6* | 30.7 ± 1.0*,*** | 23.2 ± 0.3 | 24.6 ± 0.4*,**** | 27.4 ± 0.7*,***,**** |
Uterus weight (mg) | 105 ± 8 | 108 ± 10 | 112 ± 7 | 100 ± 5 | 100 ± 7 | 109 ± 5 |
Glucose (mg/dL) | 165 ± 31 | 170 ± 18 | 185 ± 17 | 159 ± 13 | 173 ± 15 | 197 ± 11 |
Creatinine (mg/dL) | 0.29 ± 0.01 | 0.27 ± 0.01 | 0.26 ± 0.02 | 0.29 ± 0.02 | 0.28 ± 0.01 | 0.30 ± 0.02 |
17β-estradiol (pg/mL) | 286 ± 76 | 317 ± 66 | 283 ± 67 | 328 ± 59 | 286 ± 50 | 309 ± 36 |
NO−2/NO−3 (μM) | 22.2 ± 1.3 | 16.8 ± 1.0 | 13.1 ± 1.1** | 19.1 ± 1.7 | 10.5 ± 1.6**,**** | 8.3 ± 0.4**,**** |
Values are means ± SEM. n = 10 animals per group
*P < 0.05 and **P < 0.01 versus 3-month-old group of the same strain, ***P < 0.05 versus 6-month-old group of the same strain, ****P < 0.05 versus SAMR1 with same age