Recruitment of leukocytes and platelets to hepatic sinusoids 6 h following cecal ligation and puncture (CLP) in WT mice (n = 8), WT mice treated with l-NAME (n = 5), eNOS-ko mice (n = 5), iNOS-ko mice (n = 5), iNOS-ko mice treated with DetaNO (n = 5), nNOS control mice (n = 8), nNOS-ko mice (n = 5) and WT mice treated with GdCl3 (n = 5) compared to a group of WT mice following a sham procedure (n = 8). *p < 0.05 versus WT sham mice, #
p < 0.05 versus WT-CLP, ^
p < 0.05 versus iNOS-ko-CLP. WT wild type, l
-NAME
n-nitro-l-arginine methyl ester, eNOS endothelial nitric oxide synthase, iNOS inducible nitric oxide synthase, DetaNO diethylenetriamine nitric oxide, nNOS neuronal nitric oxide synthase, GdCl
3 gadolinium chloride