Table 1.
Mean arterial pressure (MAP), serum ALT concentration, and blood leukocyte and platelet counts in WT mice and in mutant mice targeting reactive oxygen species
MAP (mmHg) | ALT (IU/l) | Leukocyte count (#/μl) | Platelet count (# × 103/μl) | |
---|---|---|---|---|
WT-sham (n = 4) | 60 ± 3 | 45 ± 9 | 4380 ± 250 | 1132 ± 33 |
WT + CLP (n = 7) | 51 ± 4 | 53 ± 7 | 980 ± 150* | 544 ± 34* |
SOD-tg + CLP (n = 5) | 68 ± 7 | 52 ± 4 | 2330 ± 440* | 831 ± 57* |
gp91phox-ko + CLP (n = 5) | 59 ± 7 | 49 ± 5 | 2220 ± 340* | 688 ± 76* |
Values are mean ± SE
MAP mean arterial pressure, ALT alanine aminotransferase, SOD superoxide dismutase, CLP cecal ligation and puncture
* p < 0.05 versus WT sham