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Cytotoxic effect of ESA on either OST cells or LM8 cells, as evaluated by means of propidium iodide staining. (a) Variation of the cell viability with increasing ESA concentration during incubation for 24 hours. (b) Time courses of the cell viabilities for [ESA] = 50 μg/mL. For both set of data, mean values and standard deviations for three separate measurements are shown.
