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Representative histopathology of the colorectal mucosa (Experiment 2). When compared to (a) normal colorectal mucosa, 1.5% DSS treatment resulted in severe colitis with mucosal ulceration (b). In contrast, mucosal regeneration was observed in the colons of mice that were treated with crocin at (c) 100 ppm and (d) 200 ppm. Bars are 20 μm. H&E stain.
