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Effects of BDNF-encapsulated PGA particles in the inner ear. (a) After exposure to aminoglycoside antibiotics, fewer primary auditory neurons survived (indicated by arrows) but treatment with BDNF-encapsulated PGA particles in one ear increased the survival of these neurons (b). Treatment with the same amount of non-encapsulated PGA particles did not improve the survival of these neurons in the treated ear (d), compared to the untreated (c). Scale bar is 20 μm for (a)–(d).
