Fig. 8.
Estrogen preferentially stimulates growth of ILC in mixed tumors. BrdU incorporation of tumors from placebo and E2 supplemented mice. Pure mucinous tumor (MBCPure) and mixed mucinous tumor (MBCMixed) showing mucinous region (MUC) and invasive lobular carcinoma (ILC). Five fields were quantified for each tumor and statistical significance was determined by an unpaired two tailed t test. *p < 0.014 for tumor 1 or tumor 2 MBCPure versus MBCMixed MUC region of tumor 3 or tumor 4; +p < 0.001 for tumor 3 or tumor 4 ILC versus tumor 1 or tumor 2 MBCPure; #p < 0.001 for tumor 3 or tumor 4 MUC region versus tumor 3 or tumor 4 ILC region