Table 2.

Multivariate analysis for factors related with spontaneous rupture of hepatocellular carcinoma

Variables	HR	95%CI for HR	P value
Hypertension (presence vs absence)	7.75	2.10-28.57	0.002
Liver cirrhosis (presence vs absence)	7.16	3.96-12.97	< 0.001
Tumor size (≤ 5 cm vs > 5 cm)	3.97	2.28-6.93	< 0.001
Protrusion from the liver surface (yes vs no)	6.51	2.31-10.84	0.008
Vascular thrombus (presence vs absence)	2.90	1.48-5.70	0.002
Extrahepatic invasion (yes vs no)	3.78	2.04-7.00	< 0.001

HCC: Hepatocellular carcinoma; HR: Hazard ratio; CI: Confidence interval.