Skip to main content
. Author manuscript; available in PMC: 2013 Oct 15.
Published in final edited form as: Chem Res Toxicol. 2012 Aug 14;25(10):2179–2193. doi: 10.1021/tx300253j

Figure 7.

Figure 7

(A) UPLC-ESI/MS analysis of reaction products formed by reaction of HONH-PhIP with acetic anhydride, following SPE. The peaks in the chromatogram are PhIP (tR = 10.0), 5-HO-PhIP (tR = 10.2), N-hydroxy-N-acetyl-PhIP (tR = 10.9), and N-acetoxy-PhIP (tR = 13.7). Product ion spectra were acquired on acetylated isomers of HONH-PhIP ([M+H]+ at m/z 283.1): (B) product ion spectrum of N-acetoxy-PhIP and (C) product ion spectrum N-hydroxy-N-acetyl-PhIP.