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. Author manuscript; available in PMC: 2013 Jan 14.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Feb;19(2):327–337. doi: 10.1158/1055-9965.EPI-09-0865

Fig. 3.

Fig. 3

High ALDH1A1 expression in human bladder cancer specimens was associated with a poor prognosis for the patients. A and B. ALDH1A1+ cancer cells comprised a fraction of the CD44+ tumor cell population. Immunohistochemical study of adjacent sections of a bladder tumor for the expression of ALDH1A1 and CD44 showed that a small number of ALDH1A1+ cells (arrows in A) were present within the CD44 immunopositive tumor areas (B). C. Survival analysis of 216 patients with bladder urothelial carcinomas based on high ALDH1A1 expression status. C. Cancer-specific survival time; D. Overall survival time. P values were calculated using the log-rank test.