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. Author manuscript; available in PMC: 2013 Jan 14.
Published in final edited form as: Cancer Prev Res (Phila). 2009 Sep 8;2(9):814–822. doi: 10.1158/1940-6207.CAPR-09-0054

Fig. 4.

Fig. 4

Histopathology in synchronous CRCs with/without CIMP. A, B, and C, cribriform glandular architecture as follows: a gland with a comedo-like pattern and bridging of cells across the lumen has spaces filled with necrotic debris. These tumors (A, B, and C) showed CIMP, whereas a tumor without cribriform glandular architecture did not (D). A and B, histologic findings of a patient with two proximal CRCs; C and D, histologic findings in a patient with a proximal and a distal CRC, respectively.