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. Author manuscript; available in PMC: 2013 Jan 14.
Published in final edited form as: Circulation. 2012 Apr 21;125(21):2630–2638. doi: 10.1161/CIRCULATIONAHA.111.072694

Table 3.

2D echocardiographic-Doppler indices of RV systolic, diastolic and global function at three post-operative intervals by shunt type

Variable Post-Norwood Pre-stage II 14 months
N MBTS N RVPAS p N MBTS N RVPAS p N MBTS N RVPAS p
RV systolic function
 RV ejection fraction % (biplane pyramidal) 169 44±8 198 49±7 <0.001 127 43±8 153 45±9 0.12 104 43±7 132 43±8 0.91
 RV % area change 224 35±8 236 38±7 <0.001 167 33±7 208 34±8 0.45 134 33±7 170 32±7 0.49
 RV dP/dt, mmHg/sec 46 1032±330 41 983±336 0.50 35 865±301 47 871±335 0.93 24 798±318 28 854±402 0.59
 Tricuspid annular tissue Doppler peak systolic velocity, cm/sec 205 4.51±1.36 213 4.40±1.11 0.38 153 5.80±1.98 188 5.22±1.43 0.003 140 5.46±1.49 171 5.29±1.37 0.28
 Tricuspid annular tissue Doppler isovolumic acceleration, cm/sec/sec 41 26.6±12.8 29 26.7±10.9 0.97 57 31.8±11.3 69 31.3±12.7 0.80 71 35.2±11.7 95 35.1±11.2 0.95
RV diastolic function
 Peak tricuspid inflow E velocity, m/sec 217 0.83±0.26 224 0.79±0.23 0.09 160 0.86±0.26 199 0.86±0.25 0.87 141 0.86±0.25 179 0.86±0.25 0.91
 Peak tricuspid inflow A velocity, m/sec 91 0.66±0.21 108 0.66±0.19 0.90 94 0.80±0.21 107 0.74±0.21 0.07 80 0.72±0.22 96 0.72±0.20 0.97
 Tricuspid inflow E/A ratio 91 1.03±0.44 108 1.01±0.27 0.62 94 0.95±0.25 107 1.01±0.27 0.07 80 1.12±0.50 96 1.07±0.26 0.34
 Tricuspid annular tissue Doppler E′ velocity, cm/sec 203 7.63±2.99 212 7.61±2.84 0.96 154 8.54±3.59 187 8.98±3.45 0.25 142 8.45±3.47 172 8.95±3.87 0.23
 Tricuspid annular tissue Doppler A′ velocity, cm/sec 95 6.39±2.04 115 6.87±2.51 0.13 93 7.39±2.5 113 7.64±2.39 0.47 75 6.85±2.26 99 6.79±2.24 0.88
 E/E′ ratio 196 12.2±5.9 206 11.5±5.4 0.26 148 11.3±4.9 181 10.2±4.1 0.02 138 11.5±5.1 169 11.0±4.7 0.30
 Presence of pulmonary vein flow reversal 212 17 (8%) 216 46 (21%) <0.001 157 18 (12%) 191 33 (17%) 0.13 135 9 (7%) 176 12 (7%) 1.00
Myocardial Performance Index or Tei Index
 Blood flow Doppler calculation 200 0.38±0.18 198 0.58±0.25 <0.001 150 0.39±0.18 184 0.49±0.20 <0.001 131 0.44±0.16 168 0.44±0.18 0.96
 Tissue Doppler calculation 83 0.65±0.35 70 0.64±0.25 0.79 63 0.56±0.21 83 0.56±0.19 0.91 80 0.59±0.21 96 0.60±0.18 0.69

Data presented as mean±SD, median (inter-quartile range), or n (%). MBTS=modified Blalock-Taussig shunt; RVPAS=right ventricular-to-pulmonary artery shunt; RV=right ventricle