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. Author manuscript; available in PMC: 2013 Jan 14.
Published in final edited form as: Circulation. 2012 Apr 21;125(21):2630–2638. doi: 10.1161/CIRCULATIONAHA.111.072694

Table 5.

2D echocardiographic indices of neo-aortic and tricuspid valve dimensions and functions at three post-operative intervals by shunt type.

Variable Post-Norwood Pre-stage II 14 months
N MBTS N RVPAS p N MBTS N RVPAS p N MBTS N RVPAS p
Neo-aortic valve
Neo-aortic valve annular area (cm2)/BSA 224 4.64±1.16 228 4.21±1.13 <0.001 164 4.91±1.21 205 4.15±1.15 <0.001 137 4.31±1.08 171 4.18±1.09 0.33
Neo-aortic valve annular area, z-score 224 7.04±3.02 228 5.92±2.94 <0.001 164 8.02±3.24 205 5.99±3.09 <0.001 137 6.53±2.96 171 6.20±2.98 0.34
Neo-aortic AP valve annulus diameter (cm2)/√BSA 229 2.38±0.35 234 2.26±0.36 <0.001 168 2.44±0.35 212 2.23±0.33 <0.001 143 2.30±0.33 176 2.26±0.36 0.23
Neo-aortic AP valve annulus diameter, z-score 229 4.70±2.02 234 4.01±2.06 <0.001 168 5.60±2.26 212 4.29±2.09 <0.001 143 5.02±2.22 176 4.72±2.42 0.25
Degree of neo-aortic valve regurgitation 238 242 0.19, 0.07* 175 220 0.17, 0.73* 147 186 0.08, 0.08*
 none 132 (56%) 120 (50%) 106 (61%) 148 (67%) 65 (44%) 104 (56%)
 mild 103 (43%) 114 (47%) 66 (38%) 69 (31%) 77 (52%) 79 (43%)
 moderate 3 (1%) 8 (3%) 3 (2%) 1 (1%) 5 (3%) 3 (1%)
 severe 0 (0%) 0 (0%) 0 (0%) 2 (1%) 0 (0%) 0 (0%)
Tricuspid valve
Tricuspid annular area (cm2)/BSA 224 7.10±2.02 232 7.01±2.01 0.63 171 7.27±2.20 211 7.07±2.62 0.42 146 6.18±1.95 181 6.61±2.09 0.05
Tricuspid annular area, z-score 224 3.23±1.88 232 3.16±1.93 0.70 171 3.82±2.31 211 3.62±2.77 0.46 146 2.89±2.25 181 3.41±2.43 0.05
Tricuspid AP valve annulus diameter (cm2)/√BSA 225 2.89±0.50 235 2.86±0.48 0.60 171 2.92±0.50 213 2.85±0.58 0.22 148 2.65±0.50 182 2.79±0.51 0.02
Tricuspid AP valve annulus diameter,z-score 225 2.12±1.71 235 2.04±1.63 0.63 171 2.46±1.79 213 2.22±2.10 0.24 148 1.61±1.86 182 2.12±1.89 0.01
Tricuspid transverse valve annulus diameter (cm2)/√BSA 235 3.07±0.51 238 3.07±0.51 0.97 174 3.13±0.54 220 3.07±0.58 0.33 146 2.91±0.51 184 2.96±0.51 0.36
Tricuspid transverse valve annulus diameter, z-score 235 1.78±1.30 238 1.80±1.35 0.91 174 2.32±1.55 220 2.17±1.68 0.37 146 1.95±1.61 184 2.14±1.61 0.31
Degree of tricuspid regurgitation 237 243 0.68, 0.86* 175 222 0.09, 0.63* 148 185 0.88, 0.89*
 none 28 (12%) 29 (12%) 31 (18%) 50 (23%) 24 (16%) 27 (15%)
 mild 148 (62%) 159 (65%) 97 (55%) 114 (51%) 94 (64%) 115 (62%)
 moderate 48 (20%) 47 (19%) 33 (19%) 51 (23%) 25 (17%) 34 (18%)
 severe 13 (6%) 8 (3%) 14 (8%) 7 (3%) 5 (3%) 9 (5%)

Data presented as mean±SD or n (%). MBTS=modified Blalock-Taussig shunt; RVPAS=right ventricular-to-pulmonary artery shunt

*

P-values obtained from Fisher’s exact test and Mantel-Haenszel test of trend respectively.