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The structure of mouse and rat BDNF gene. BDNF gene consists of eight 5’ exons (I-VIII) and one 3’ exon (IX). Introns in the gene are presented as straight horizontal lines. The protein-coding region is shown as a dark box, and the non-coding exon regions are shown as open boxes. Three alternative splicing sites (A, B and C) in exon II and the two poly-adenylation sites (polyA site) are indicated with arrows. Exon IXA is the 5’ extended coding exon. Adapted from Aid et al., 2007 [35].
