Figure 6.

α-NF exerted synergistic suppressive effects with SB203580, a selective p38 inhibitor, on adipogenicgenes protein expression during 3T3-L1 cells differentiation. A. SB203580, a p38 selective inhibitor, has slightlynegative effects on mRNA expression of mid-phase differentiation genes, PPARγ, C/EBPα, but exhibited synergisticlyeffects with α-NF on late phase differentiation marker—FABP4 and Glut4. B. α-NF exerted substainly inhibitory effectson PPARγ and Glut4 protein expression and synergisticaly with SB203580.