Table 6.
One way ANOVA of the mean ± S.E haematological parameters of the rats administered 12 mg/Kg body weight (Group C) of HAART on Days 5, 10, 15, 20, and 25.
| Parameter | Day 5 | Day 10 | Day 15 | Day 20 | Day 25 |
|---|---|---|---|---|---|
| RBC (×1012/L) | 7.23 ± 0.13 | 6.89 ± 0.14 | 9.14 ± 0.61 | 7.86 ± 0.31 | 8.95 ± 0.20* |
| HB (g/dL) | 12.55 ± 0.25 | 12.55 ± 0.45 | 14.55 ± 1.15 | 13.70 ± 0.40 | 16.20 ± 0.50* |
| PCV (L/L) | 39.00 ± 1.00 | 42.50 ± 1.50 | 57.40 ± 5.40 | 51.00 ± 1.00 | 59.60 ± 2.70* |
| MCHC (g/dL) | 32.00 ± 1.20 | 29.70 ± 0.30 | 25.50 ± 0.50 | 26.70 ± 0.40 | 27.50 ± 0.50** |
| MCH (pg) | 57.50 ± 0.50 | 62.00 ± 1.00 | 62.95 ± 1.45 | 65.30 ± 1.70 | 66.70 ± 4.50 |
| MCV (fL) | 17.30 ± 0.10 | 18.15 ± 0.25 | 15.90 ± 0.20 | 17.45 ± 0.15 | 18.15 ± 0.95 |
| RETICS (%) | 1.30 ± 0.30 | 1.15 ± 0.15 | 1.60 ± 0.20 | 0.95 ± 0.05 | 1.30 ± 0.10 |
| PLAT (×109/L) | 571.00 ± 72.00 | 370.00 ± 232.00 | 800.50 ± 20.50 | 787.50 ± 1.50 | 791.00 ± 29.00** |
| WBC (×109/L) | 6.85 ± 1.95 | 9.30 ± 1.10 | 5.95 ± 1.05 | 7.65 ± 2.05 | 8.80 ± 2.70 |
| NEUT (%) | 20.00 ± 4.00 | 24.50 ± 3.50 | 27.00 ± 3.00 | 25.50 ± 2.50 | 13.50 ± 5.50*** |
| LYMPH (%) | 78.50 ± 3.50 | 75.50 ± 3.50 | 72.00 ± 4.00 | 74.5 ± 2.50 | 86.50 ± 5.50*** |
| EOS (%) | 0.50 ± 0.50 | 0.50 ± 0.50 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 |
| MONO (%) | 1.00 ± 1.00 | 0.00 ± 0.00 | 1.00 ± 1.00 | 0.00 ± 0.00 | 0.00 ± 0.00 |
| BAS (%) | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 |
RBC: red blood cell, HB: haemoglobin concentration, PCV: packed cell volume, MCHC: mean cell haemoglobin concentration, MCV: mean cell volume, MCH: mean cell haemoglobin, RETICS: reticulocytes, PLAT: platelets, WBC: white blood cell, NEUT: neutrophils, LYMPH: lymphocytes, EOS: eosinophils, BAS: basophils.
*Compared with the control group *P < 0.05, **P < 0.01, ***P < 0.001.