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Representative Western blots of SIRT1, PGC-1α, and ERR-1α. Representative blots from the kidney are shown. (a) Western blot analysis showed that aging markedly decreased SIRT1, PGC-1α, and ERR-1α protein levels in the 24 M group compared with other groups. Quantitative analyses of the results are shown (b–d). *P < 0.05 versus 2 M, **P < 0.01 versus 2 M.
