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. 2012 Sep 13;1(2):218–229. doi: 10.1002/cam4.32

Figure 1.

Figure 1

Immunohistochemical analysis of RFP in epithelial ovarian cancer. (A) RFP expression in serous, mucinous, endometrioid, and clear cell adenocarcinomas. To evaluate RFP expression, the staining intensity was scored as 0 (negative), 1 (weak), 2 (medium), or 3 (strong). The staining extent was scored as 0 (<10%), 1 (10–30%), 2 (30–50%), or 3 (>50%) in relation to the entire cancer area. The sum of scores for the staining intensity and staining extent was used as the staining score (0–6) for RFP. Staining score 0–2, negative; 3–6, positive. Representative images with staining scores 0 (left), 3 (middle), and 6 (right) are shown. Scale bars: 200 μm. (B) Kaplan–Meier survival curves of patients with epithelial ovarian cancer stratified by RFP expression. The 5-year overall survival rate: all cases (n = 92).