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. 2012 Oct 2;1(3):295–305. doi: 10.1002/cam4.35

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© 2012 The Authors. Published by Blackwell Publishing Ltd.

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

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CHAC1 suppression inhibits nisin-induced DNA fragmentation. (A) Immunoblot showing CHAC1 expression in UM-SCC-17B cells after treatment with nisin (80 μg/mL) for 24 h. β-Actin served as loading control. (B) DNA fragmentation, (C) fold change in proliferation, and (D) calcium influx levels in UM-SCC-17B cells after transfection with CTRL siRNA or CHAC1 siRNA and treated with nisin (80 μg/mL) for 24 h. Inset, immunoblot showing CHAC1 levels after transfection with CHAC1 siRNA. P values for each data set are indicated individually.