Table 2.

Pressure-volume analysis of baseline systolic and diastolic function

	Con	HF	HF-TR
Systolic function
LVESV, ml	54 ± 8	93 ± 9*	72 ± 9
LVESP, mmHg	101 ± 5	112 ± 13	106 ± 3
SW, J	0.41 ± 0.10	0.69 ± 0.05*	0.72 ± 0.06*
CO, l/min	3.6 ± 0.8	5.9 ± 0.5	5.9 ± 1.0
RPP, beats·min−1· mmHg	8,912 ± 591	11,764 ± 1,669	9,019 ± 689
SV, ml	40 ± 9	57 ± 3	68 ± 10
EF, %	42 ± 3	38 ± 3	49 ± 6
Diastolic function
LVEDV, ml	94 ± 16	150 ± 8*	140 ± 8*
LVEDP, mmHg	11 ± 1	14 ± 2	15 ± 2
τ Glantz, ms	53 ± 3	82 ± 6*	70 ± 6
Cardiac Efficiency
SW/MV̇o2	0.38 ± 0.11	0.56 ± 0.12	0.97 ± 0.19*

Values are means ± SE. Con, control; HF, heart failure sedentary; HF-TR, heart failure exercise trained; LVESV, left ventricular end-systolic volume; LVESP, left ventricular end-systolic pressure; SW, stroke work; CO, cardiac output; RPP, rate-pressure product; SV, stroke volume; EF, ejection fraction; LVEDV, left ventricular end-diastolic volume; LVEDP, left ventricular end-diastolic pressure; τ, time constant of left ventricular pressure decay; MV̇o₂, myocardial O₂ consumption; SW/MV̇o₂, ratio of SW to MV̇o₂.

^*Significance is indicated at P < 0.05 vs. Con.