Table 4.

Hemodynamic and blood-gas variables at baseline and during increasing pressure loads

	80 mmHg	90 mmHg	100 mmHg	120 mmHg
MAP, mmHg
Con	78 ± 3	89 ± 2	98 ± 1	117 ± 1
HF	83 ± 1	91 ± 1	100 ± 1	117 ± 4
HF-TR	81 ± 2	92 ± 2	99 ± 2	116 ± 3
HR, beats/min
Con	88 ± 3	80 ± 6	71 ± 4	71 ± 8
HF†	104 ± 4*	98 ± 6	99 ± 11	109 ± 16*
HF-TR	85 ± 6	86 ± 6	81 ± 6	80 ± 7
CBF, ml·min−1·g−1
Con	0.27 ± 0.02	0.31 ± 0.03	0.38 ± 0.04	0.58 ± 0.11
HF	0.30 ± 0.07	0.30 ± 0.07	0.36 ± 0.06	0.47 ± 0.11
HF-TR	0.20 ± 0.04	0.26 ± 0.06	0.28 ± 0.06	0.42 ± 0.10
MV̇o2, μmol O2·min−1·g−1
Con	1.10 ± 0.06	1.36 ± 0.10	1.74 ± 0.12	1.88 ± 0.21
HF	1.40 ± 0.22	1.35 ± 0.29	1.67 ± 0.21	2.05 ± 0.52
HF-TR	0.84 ± 0.12	0.95 ± 0.14	1.17 ± 0.11	1.48 ± 0.27
Arterial Po2, Torr
Con	483 ± 25	536 ± 16	547 ± 7	561 ± 16
HF	498 ± 30	497 ± 37	502 ± 39	516 ± 20
HF-TR	527 ± 28	540 ± 25	521 ± 17	555 ± 10
Coronary venous Po2, Torr
Con	25 ± 2	23 ± 1	27 ± 2	31 ± 4
HF	22 ± 1	23 ± 1	30 ± 3	31 ± 3
HF-TR	22 ± 1	23 ± 2	25 ± 2	32 ± 3
Coronary venous So2, %
Con	30 ± 2	32 ± 1	39 ± 4	57 ± 7
HF	27 ± 4	29 ± 3	38 ± 6	50 ± 7
HF-TR	30 ± 3	33 ± 7	36 ± 7	49 ± 7
Hb, g/100 ml
Con	8.2 ± 0.2	9.0 ± 0.2	10.1 ± 0.4	11.3 ± 0.8
HF	9.1 ± 0.6	9.0 ± 0.5	10.8 ± 1.0	11.7 ± 0.9
HF-TR	8.5 ± 0.5	8.7 ± 0.5	9.7 ± 0.7	10.6 ± 1.0

Values are means ± SE. MAP, mean arterial pressure; CBF, coronary blood flow; Po₂, O₂ pressure; So₂, O₂ saturation; Hb, hemoglobin.

^*Significance is indicated at P < 0.05 vs. Con, same pressure load.

^†P < 0.05 vs. Con (repeated-measures ANOVA; group main effect).