Table 3.

Gestational diabetes mellitus (GDM) risk according to quartiles of early pregnancy maternal serum RBP4 concentrations stratified by advanced maternal age

Serum RBP4 (μg/ml)	GDM N= 173	Controls N= 187	Unadjusted OR (95%CI)	Adjusted OR (95%CI) *
	N (%)	N (%)
Maternal Age ≥35 years
Quartile 1 (<31.2)	11 (13.1)	16 (22.9)	Referent	Referent
Quartile 2 (31.2 - 38.2)	14 (16.7)	18 (25.7)	1.13 (0.40-3.19)	0.96 (0.32-2.89)
Quartile 3 (38.3 - 46.3)	22 (26.2)	16 (22.9)	2.00 (0.73-5.44)	1.92 (0.67-5.51)
Quartile 4 (≥ 46.4)	37 (44.0)	20 (28.6)	2.69 (1.05-6.89)	2.40 (0.89-6.45)
p-value for the trend			p=0.02	p=0.03
Maternal Age< 35 years
Quartile 1 (<31.2)	20 (22.5)	30 (25.6)	Referent	Referent
Quartile 2 (31.2 - 38.2)	25 (28.1)	28 (23.9)	1.33 (0.61-2.92)	0.98 (0.41-2.35)
Quartile 3 (38.3 - 46.3)	21 (23.6)	32 (27.4)	0.98 (0.44-2.16)	1.03 (0.43-2.45)
Quartile 4 (≥ 46.4)	23 (25.8)	27 (23.1)	1.27 (0.57-2.82)	1.02 (0.42-2.45)
p-value for the trend			0.8	0.93

^*OR and 95%CI adjusted for maternal race/ethnicity, family history of diabetes, and pre-pregnancy overweight status.

Number (%)