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. 2012 Dec 27;5:700. doi: 10.1186/1756-0500-5-700

Table 1.

Accuracy of primary data (BCQDB) in comparison to external databases, period 1996-97

 
 Secondary data
 Primary data
 95% Confidence interval
 Test-statistic
Variable-level GER (θ1) BCQDB (θ2) Lower bound (θ2) Upper bound (θ2) p-value
00-49 years
 21.4
 24.4
 19.4
 30.1
 ns
50-69 years
 50.5
 43.6
 37.6
 49.8
 0.024
≥ 70 years
 28.1
 32.0
 26.4
 37.9
 ns
pTis (non-invasive)
 4.3
 4.5
 2.4
 7.7
 ns
pT1 (≤ 2cm)
 47.4
 53.0
 46.8
 59.1
 ns
pT2 (≤ 5cm)
 35.8
 30.8
 25.3
 36.8
 ns
pT3 (> 5cm)
 4.7
 2.6
 1.1
 5.3
 ns
pT4 (involving other areals)
 7.8
 9.0
 5.9
 13.1
 ns
pN+
 37.0
 32.7
 27.1
 38.7
 ns
Involved lymph nodes 0
 60.9
 63.4
 57.0
 69.6
 ns
Involved lymph nodes 1-3
 20.1
 19.3
 14.5
 24.9
 ns
Involved lymph nodes 4-9
 11.8
 10.5
 6.9
 15.1
 ns
Involved lymph nodes >10
 7.2
 6.7
 3.9
 10.7
 ns
Stage 0
 4.2
 4.5
 2.4
 7.7
 ns
Stage 1
 36.0
 38.7
 32.8
 44.9
 ns
Stage 2a
 28.5
 27.8
 22.5
 33.6
 ns
Stage 2b
 16.4
 12.0
 8.4
 16.6
 ns
Stage 3a
 4.2
 2.3
 0.8
 4.8
 ns
Stage 3b
 6.3
 8.6
 5.6
 12.7
 ns
Stage 4
 4.5
 6.0
 3.5
 9.6
 ns
Grading 1 (G1)
 11.3
 7.9
 4.9
 11.9
 ns
Grading 2 (G2)
 55.8
 43.3
 37.1
 49.6
 <0.001
Grading 3 (G3)
 c32.9
 48.8
 42.5
 55.1
 <0.001
ERPR+
 82.0
 83.5
 78.4
 87.7
 ns
Variable-level
 GKR (θ1)
 BCQDB (θ2)
 Lower bound (θ2)
 Upper bound (θ2)
 p-value
00-49 years
 20.4
 24.4
 19.4
 30.1
 ns
50-69 years
 49.0
 43.6
 37.6
 49.8
 ns
≥ 70 years
 30.6
 32.0
 26.4
 37.9
 ns
Left side
 50.6
 56.0
 49.8
 62.1
 ns
Right side
 47.7
 44.0
 37.9
 50.2
 ns
Breast quadrant I
 48.6
 46.6
 40.5
 52.8
 ns
Breast quadrant II
 12.3
 11.3
 7.7
 15.7
 ns
Breast quadrant III
 9.1
 11.7
 8.1
 16.1
 ns
Breast quadrant IV
 5.6
 8.6
 5.6
 12.7
 ns
Multifocal
 16.6
 17.3
 12.9
 22.4
 ns
Mamille
 7.8
 4.5
 2.4
 7.7
 0.045
Non-invasive tumor
 5.8
 4.5
 2.4
 7.7
 ns
Stage 0
 6.1
 4.5
 2.4
 7.7
 ns
Stage 1
 38.4
 38.7
 32.8
 44.9
 ns
Stage 2
 41.9
 39.8
 33.9
 46.0
 ns
Stage 3
 8.0
 10.9
 7.4
 15.3
 ns
Stage 4
 5.6
 6.0
 3.5
 9.6
 ns
Stage 0 | 0–49 years
 7.0
 7.7
 2.5
 17.0
 ns
Stage 1 | 0–49 years
 38.0
 36.9
 25.3
 49.8
 ns
Stage 2 | 0–49 years
 43.7
 46.2
 33.7
 59.0
 ns
Stage 3 | 0–49 years
 6.5
 6.2
 1.7
 15.0
 ns
Stage 4 | 0–49 years
 4.8
 3.1
 0.4
 10.7
 ns
Stage 0 | 50–69 years
 6.9
 4.3
 1.4
 9.8
 ns
Stage 1 | 50–69 years
 39.4
 41.4
 32.3
 50.9
 ns
Stage 2 | 50–69 years
 41.0
 42.2
 33.1
 51.8
 ns
Stage 3 | 50–69 years
 7.7
 6.9
 3.0
 13.1
 ns
Stage 4 | 50–69 years
 5.0
 5.2
 1.9
 10.9
 ns
Stage 0 | ≥70 years
 4.1
 2.4
 0.3
 8.2
 ns
Stage 1 | ≥70 years
 36.9
 36.5
 26.3
 47.6
 ns
Stage 2 | ≥70 years
 42.2
 31.8
 22.1
 42.8
 ns
Stage 3 | ≥70 years
 9.7
 20.0
 12.1
 30.1
 <0.001
Stage 4 | ≥70 years 7.1 9.4 4.2 17.7 ns

(θ) Population parameter in percent, (GER) Mean of a five German regions for 1996–97 (Engel et al., 2002).

(BCQDB) Breast Cancer Query Database, Marburg, Germany; (GKR) Common Cancer Registers of the states.

Berlin, Brandenburg, Mecklenburg-Vorpommern, Saxony-Anhalt, Saxony and Thuringa (Stabenow & Eisinger, 2001).

(pN+) Pathological assessment of metastases in lymph nodes, (ERPR) Estrogen-Progesterone-Receptors.

(Multifocal) All quadrants involved, (Stage | age) Percent of patients with stage number conditional on age groups.