Table 2.
The estimated minimal sample number per group for quantitative analysis based on spectrum count method, where power is the power of statistical test, α is the significance level, and π refers to the estimated proportion of truly differentially expressed proteins among all of the identified proteins
| fold change | power | α | π | FDR | normal group | male group | female group |
|---|---|---|---|---|---|---|---|
| 2 |
0.8 |
0.001 |
0.05 |
2.31% |
20 |
18 |
15 |
| |
0.8 |
0.005 |
0.1 |
5.33% |
16 |
14 |
12 |
| |
0.8 |
0.01 |
0.2 |
4.76% |
14 |
12 |
10 |
| |
0.9 |
0.001 |
0.05 |
2.06% |
24 |
22 |
17 |
| |
0.9 |
0.005 |
0.1 |
4.76% |
19 |
17 |
14 |
| |
0.9 |
0.01 |
0.2 |
4.26% |
17 |
15 |
12 |
| 1.5 |
0.8 |
0.001 |
0.05 |
2.31% |
71 |
63 |
49 |
| |
0.8 |
0.005 |
0.1 |
5.33% |
56 |
49 |
39 |
| |
0.8 |
0.01 |
0.2 |
4.76% |
49 |
43 |
34 |
| |
0.9 |
0.001 |
0.05 |
2.06% |
87 |
77 |
60 |
| |
0.9 |
0.005 |
0.1 |
4.76% |
69 |
61 |
48 |
| 0.9 | 0.01 | 0.2 | 4.26% | 62 | 54 | 43 |