Table 3.
The estimated minimal sample number per group for five proteins based on western blot, where power is the power of statistical test, α is the significance level, and π refers to the estimated proportion of truly differentially expressed proteins among all of the identified proteins.
|
fold change |
power |
α |
π |
FDR |
alpha 1 |
ceruloplasmin |
beta-2 |
|---|---|---|---|---|---|---|---|
| antitrypsin | microglobulin | ||||||
| 2 |
0.8 |
0.001 |
0.05 |
2.31% |
26 |
38 |
33 |
| |
0.8 |
0.005 |
0.1 |
5.33% |
20 |
30 |
26 |
| |
0.8 |
0.01 |
0.2 |
4.76% |
18 |
26 |
22 |
| |
0.9 |
0.001 |
0.05 |
2.06% |
31 |
46 |
39 |
| |
0.9 |
0.005 |
0.1 |
4.76% |
25 |
37 |
31 |
| |
0.9 |
0.01 |
0.2 |
4.26% |
22 |
33 |
28 |
| 1.5 |
0.8 |
0.001 |
0.05 |
2.31% |
93 |
143 |
121 |
| |
0.8 |
0.005 |
0.1 |
5.33% |
73 |
111 |
95 |
| |
0.8 |
0.01 |
0.2 |
4.76% |
64 |
98 |
83 |
| |
0.9 |
0.001 |
0.05 |
2.06% |
113 |
174 |
148 |
| |
0.9 |
0.005 |
0.1 |
4.76% |
91 |
139 |
118 |
| 0.9 | 0.01 | 0.2 | 4.26% | 81 | 124 | 105 |